Mood Dysfunction Improved In Gene Knockout Mice

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Removing the PKCI/HINT1 gene from mice has an anti-depressant-like and anxiolytic-like effect. Researchers writing in the open access journal BMC Neuroscience applied a battery of behavioral tests to the PKCI/HINT1 knockout animals, concluding that the deleted gene may have an important role in mood regulation.

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Faulty Body Clock May Make Kids Bipolar

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Malfunctioning circadian clock genes may be responsible for bipolar disorder in children. Researchers writing in the open access journal BMC Psychiatry found four versions of the regulatory gene RORB that were associated with pediatric bipolar disorder.

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Mental Health America Applauds Bipartisan Legislation To Help Treat Depression And Bipolar Disorders

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Mental Health America is applauding legislation introduced by a bipartisan group of U.S. Senators to establish national centers of excellence for the treatment of depression and bipolar disorders. The centers will create a national network to help diagnose people in need and improve access to evidence-based, quality care. The bill, called the “ENHANCED Act” was introduced by U.S. Senators Debbie Stabenow (D-Mich.

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Break-through Preventative Care Program For People Living With Bipolar Disorder

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A major breakthrough in mental health has been developed, a cooperative venture between the National Bipolar Foundation and the MedicAlert Foundation; a preventative care program called “Safe ’til Stable.” It provides vital medical information to emergency responders in time of need through our live 24-hour emergency response service. In a medical emergency, this can help reduce the trauma experienced by individuals impacted with bipolar disorder.

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Funding Supports ADA Technologies’ Development Of Home Monitor For Bipolar Disorder

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ADA Technologies, Inc. (ADA) received a $189,886 grant from the National Institute of Mental Health to develop a home lithiummonitor for use by patients with bipolar disorder. The testing tool would allow reliable, routine at-home monitoring of blood lithium concentrations, enabling individuals with bipolar disorder to conveniently and effectively manage their care.

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UNC Study Pinpoints Gene Controlling Number Of Brain Cells

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The finding suggests that a single gene, called GSK-3, controls the signals that determine how many neurons actually end up composing the brain. This has important implications for patients with neuropsychiatric illness, as links have recently been drawn between GSK-3 and schizophrenia, depression and bipolar disorder.

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Young Adults May Outgrow Bipolar Disorder

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Bipolar disorder, or manic-depression, causes severe and unusual shifts in mood and energy, affecting a person’s ability to perform everyday tasks. With symptoms often starting in early adulthood, bipolar disorder has been thought of traditionally as a lifelong disorder. Now, University of Missouri researchers have found evidence that nearly half of those diagnosed between the ages of 18 and 25 may outgrow the disorder by the time they reach 30.

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Yale Researchers Succeed In Repairing Brain Damage Caused By Chronic Stress, Lead Poisoning, Potential Implications For Bipolar Disorder

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Yale University researchers report in the Proceedings of the National Academy of Sciences (September 7-11 edition) that damage to the brain caused by chronic stress or lead poisoning can be repaired by blocking a key molecular pathway. Research shows that rats exposed to chronic stress develop damage to the prefrontal cortex. This is an area of the brain essential to working memory, impulse control and the ability to stay focused on tasks.

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Yale Researchers Repair Brain Damage Caused By Chronic Stress Work Has Implications For Bipolar Disorder, PTSD

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Damage to the brain caused by chronic stress or lead poisoning can be repaired by blocking a key molecular pathway, Yale University researchers report in the September 7-11 edition of the Proceedings of the National Academy of Sciences. Rats subjected to chronic stress develop damage to the prefrontal cortex, an area of the brain crucial to working memory, impulse control and the ability to stay focused on tasks.

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AstraZeneca Traveling Exhibit Helps Americans Understand And Manage Bipolar Depression

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As part of its ongoing effort to support bipolar depression awareness and education, AstraZeneca (NYSE: AZN) is bringing The Bipolar Journey: Living With Bipolar Depression interactive exhibit to patients and caregivers across America. Those who have been touched by bipolar depression — the depressive phase of bipolar disorder — are encouraged to visit a nearby exhibit site and learn more about living with this disease and how to help manage it.

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