In the new Swedish-Finnish study, published in Nature Genetics, the researchers identified five loci that predispose to an SLE-related disease in Nova Scotia duck tolling retrievers. The study indicates that the homogeneity of strong genetic risk factors within dog breeds make dogs an excellent model in which to identify pathways involved in human complex diseases…
Investigators have identified a biomarker that could help doctors select patients with rheumatoid arthritis who will benefit from therapy with drugs such as Enbrel, a tumor necrosis factor (TNF)-antagonist drug…
You’d think folks who’ve had knee replacement surgery — finally able to walk and exercise without pain — would lose weight instead of put on pounds, but surprisingly that’s not the case, according to a University of Delaware study…
A researcher from Northwestern University Feinberg School of Medicine has invented a novel way to halt and even reverse rheumatoid arthritis. He developed an imitation of a suicide molecule that floats undetected into overactive immune cells responsible for the disease. Whimsically referred to as Casper the Ghost, the stealthy molecule causes the immune cells to self-destruct…
A recent study by researchers from the Cleveland Clinic found that the overall mortality rate in the U.S. for all pediatric patients with rheumatic diseases was not worse than the age and sex-adjusted population. Furthermore, mortality rates were significantly lower than reported in previous studies of rheumatic diseases and conditions that are associated with increased mortality…
Researchers from University Hospital in Umea, Sweden, have identified several cytokines, cytokine-related factors, and chemokines that increase significantly prior to rheumatoid arthritis (RA) disease onset. These findings confirm those of earlier studies which suggest that the risk of developing RA can be predicted and disease progression may be prevented…
Bristol-Myers Squibb Company (NYSE: BMY) announced that on 20 January 2010, the European Commission approved ORENCIA® (abatacept) in combination with methotrexate for the treatment of moderate to severe active polyarticular juvenile idiopathic arthritis (pJIA) in paediatric patients six years of age and older who have had an insufficient response to other DMARDS, including …
The links between autoimmune diseases, infections, genetics and the environment are complex and mysterious…
Osteoarthritis (OA) is one of the ten most disabling diseases in the developed world and is set to become more of a financial burden on health services as average life expectancy increases. OA is the most common form of arthritis, affecting nearly 27 million Americans or 12.1% of the adult population of the United States, according to Laurence et al…
Researchers at Geisinger Medical Center recently received funding totaling more than $44,000 from a Geisinger Health System (GHS) – NYU Langone Medical Center (NYULMC) collaborative project focusing on personalized healthcare…
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